not in the least; to completely lack
Zhège wèntí duì tā lái shuō háowú nándù.
这个问题对他来说毫无难度。
This problem poses no difficulty to him.
Tā duì zhège jìhuà háowú xìngqù.
他对这个计划毫无兴趣。
He has no interest in this plan at all.
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